Head: Assoc. Prof. Michał Obuchowski, M.D., Ph.D.
Assoc. Prof. Michał Obuchowski, M.D., Ph.D.
Field of scientific activity:
Molecular biology of Bacillus subtilis spore development and germination. Use of the spore as universal carrier for peptides and proteins useful in biotechnology industry and medical sciences. Rapid detection of pathogenic bacteria in environmental and medical samples.
Main achievements:
Elucidation of the biological role of the protein phosphatase PrpE during spore formation in Bacillus subtilis. Successful use the spores as carriers for enzymes and antigens coming from Helicobacter pylori and Clostridium difficile. Development of rapid test based on Real-Time PCR for Acinetobacter baumannii detection.
Scientific and service offer:
We have some expertise in the variety of the methods useful for study microorganisms at the molecular level.
International Projects:
Spore-based oral vaccine against Helicobacter pylori carried on in collaboration with University of Frederic II in Naples, Italy.
Commercialization and technology transfer:
Patent applications:- Oral vaccine based on the spores of Bacillus subtilis against Helicobacter pylori
- Penta-peptide derivatives of the bensoxasol as new antimicrobial and antifungal agents
- Oral vaccination against Clostridium difficile infections
- Set of the probes for rapid detection of Acinetobacter baumannii
Contact details
Laboratory of Molecular Bacteriology
Assoc. Prof. Michał Obuchowski, M.D., Ph.D.
obuchowk@biotech.ug.gda.pl
+48 58 349 14 38